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Analysis of mortality risk factors in children with severe adenovirus pneumonia: A single-center retrospective study
- Source :
- Pediatrics and Neonatology, Vol 64, Iss 3, Pp 280-287 (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- Background: Human adenovirus (HAdV) is one of the most common viruses causing respiratory infections among young children. Most adenovirus infections are mild and self-limited; however, these infections may occasionally cause severe pneumonia and even death. The mortality risk factors for severe adenovirus pneumonia are not completely clear. This study aimed to evaluate the mortality risk factors in children with severe adenovirus pneumonia. Methods: A retrospective study of children with severe adenovirus pneumonia hospitalized in Guangzhou Women and Children's Hospital between July 2018 and January 2020 was performed. Binary logistic regression analysis was used to identify independent mortality risk factors for severe adenovirus pneumonia after univariate analysis. Results: Our study included 189 patients (123 males and 66 females). Among them, 13 patients did not survive with a mortality of 6.88%. In multivariate analysis, the independent mortality risk factors in children with severe adenovirus pneumonia were age less than 1 year (OR = 18.513, 95% CI: 2.157–158.883, p = 0.008), hypoxia (OR = 62.335, 95% CI: 2.385–1629.433, p = 0.013), and thrombocytopenia (platelet
- Subjects :
- children
mortality
risk factors
severe adenovirus pneumonia
Pediatrics
RJ1-570
Subjects
Details
- Language :
- English
- ISSN :
- 18759572
- Volume :
- 64
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Pediatrics and Neonatology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5aa42c1afa334ba89785e2163926180e
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.pedneo.2022.06.016