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Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
- Source :
- European Journal of Case Reports in Internal Medicine (2021)
- Publication Year :
- 2021
- Publisher :
- SMC MEDIA SRL, 2021.
-
Abstract
- We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenous immunoglobulin was added. One year after initial treatment was started, as levels of creatine kinase (CK) were >1000 U/l, treatment with rituximab was added. Despite a 3-year delay before treatment, muscle strength improved even though CK levels remain elevated.
- Subjects :
- Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 22842594
- Database :
- Directory of Open Access Journals
- Journal :
- European Journal of Case Reports in Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5a874346f7b4f559fccb83316447ffe
- Document Type :
- article
- Full Text :
- https://doi.org/10.12890/2021_002672