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Multiple applications of metal-organic frameworks (MOFs) in the treatment of orthopedic diseases

Authors :
Ziwen Zhao
Chenxu Wang
Aiguo Liu
Ning Bai
Bo Jiang
Yuanfu Mao
Ting Ying
Daming Dong
Chengqing Yi
Dejian Li
Source :
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

Pharmacologic treatment of orthopedic diseases is a common challenge for clinical orthopedic surgeons, and as an important step in the stepwise treatment of orthopedic diseases, it is often difficult to achieve satisfactory results with existing pharmacologic treatments. Therefore, it is increasingly important to find new ways to effectively improve the treatment pattern of orthopedic diseases as well as to enhance the therapeutic efficacy. It has been found that metal-organic frameworks (MOFs) possess the advantages of high specific surface area, high porosity, chemical stability, tunability of structure and biocompatibility. Therefore, MOFs are expected to improve the conventional traditional treatment modality for bone diseases. This manuscript reviewed the applications of MOFs in the treatment of common clinical bone diseases and look forward to its future development.

Details

Language :
English
ISSN :
22964185
Volume :
12
Database :
Directory of Open Access Journals
Journal :
Frontiers in Bioengineering and Biotechnology
Publication Type :
Academic Journal
Accession number :
edsdoj.5a40a6e13bd9478eaac1f09392fcf369
Document Type :
article
Full Text :
https://doi.org/10.3389/fbioe.2024.1448010