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The comorbidity of increased arterial stiffness and microalbuminuria in a survey of middle-aged adults in China

Authors :
Rujia Miao
Liuxin Wu
Ping Ni
Yue Zeng
Zhiheng Chen
Source :
BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-8 (2018)
Publication Year :
2018
Publisher :
BMC, 2018.

Abstract

Abstract Background Increased arterial stiffness (iAS) and microalbuminuria (MAU), which may occur simultaneously or separately in the general population and share similar risk factors, are markers of macro- and microvascular injuries. Our research investigated the comorbidity of iAS and MAU in the middle-aged population and examined the heterogeneous effects of metabolic risk factors on iAS and MAU. Methods We selected 11,911 individuals aged 45 to 60 years who underwent a health examination at the 3rd Xiangya Hospital between 2010 and 2014. Metabolic syndrome (MetS) was determined according to IDF/NHLBI/AHA-2009 criteria. Multinomial logistic regression was applied to evaluate the influence of MetS, components of MetS and clusters of MetS on the co-occurrence (MAU(+)/iAS(+)) or non-co-occurrence (MAU(+)/iAS(−) and MAU(−)/iAS(+)) of MAU and iAS. Results Reference group was MAU(−)/iAS(−). A positive effect of MetS on the presence of MAU(+)/iAS(−), MAU(−)/iAS(+), or MAU(+)/iAS(+) is listed in ascending order based on odds ratios (ORs = 2.11, 2.41, 4.61, respectively; P

Details

Language :
English
ISSN :
14712261
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Cardiovascular Disorders
Publication Type :
Academic Journal
Accession number :
edsdoj.5a2d34eeec940cf938bf5969d24f1de
Document Type :
article
Full Text :
https://doi.org/10.1186/s12872-018-0817-1