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The comorbidity of increased arterial stiffness and microalbuminuria in a survey of middle-aged adults in China
- Source :
- BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-8 (2018)
- Publication Year :
- 2018
- Publisher :
- BMC, 2018.
-
Abstract
- Abstract Background Increased arterial stiffness (iAS) and microalbuminuria (MAU), which may occur simultaneously or separately in the general population and share similar risk factors, are markers of macro- and microvascular injuries. Our research investigated the comorbidity of iAS and MAU in the middle-aged population and examined the heterogeneous effects of metabolic risk factors on iAS and MAU. Methods We selected 11,911 individuals aged 45 to 60 years who underwent a health examination at the 3rd Xiangya Hospital between 2010 and 2014. Metabolic syndrome (MetS) was determined according to IDF/NHLBI/AHA-2009 criteria. Multinomial logistic regression was applied to evaluate the influence of MetS, components of MetS and clusters of MetS on the co-occurrence (MAU(+)/iAS(+)) or non-co-occurrence (MAU(+)/iAS(−) and MAU(−)/iAS(+)) of MAU and iAS. Results Reference group was MAU(−)/iAS(−). A positive effect of MetS on the presence of MAU(+)/iAS(−), MAU(−)/iAS(+), or MAU(+)/iAS(+) is listed in ascending order based on odds ratios (ORs = 2.11, 2.41, 4.61, respectively; P
Details
- Language :
- English
- ISSN :
- 14712261
- Volume :
- 18
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- BMC Cardiovascular Disorders
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5a2d34eeec940cf938bf5969d24f1de
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s12872-018-0817-1