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New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

Authors :
Chang-Yih Duh
Shang-Kwei Wang
Source :
Marine Drugs, Vol 10, Iss 2, Pp 306-318 (2012)
Publication Year :
2012
Publisher :
MDPI AG, 2012.

Abstract

Six new cembranolides, michaolides L–Q (1–6), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 1–7 and their cytotoxicity against selected cell lines were evaluated.

Subjects

Subjects :
Lobophytum michaelae
cembranolides
cytotoxicity
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
10020306 and 16603397
Volume :
10
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Marine Drugs
Publication Type :
Academic Journal
Accession number :
edsdoj.5a198059af19466c873a1e753ef993ae
Document Type :
article
Full Text :
https://doi.org/10.3390/md10020306
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