VALUE OF PLASMA NEUTROPHIL-TO-LYMPHOCYTE RATIO COMBINED WITH GLOBAL REGISTRY OF ACUTE CORONARY EVENTS SCORE IN EVALUATING THE LONG-TERM PROGNOSIS OF PATIENTS WITH NON-ST-ELEVATION MYOCARDIAL INFARCTION

Objective To investigate the value of plasma neutrophil-to-lymphocyte ratio (NLR) combined with global registry of acute coronary events (GRACE) score in evaluating the long-term prognosis of patients with non-ST-elevation myocar-dial infarction (NSTEMI). Methods An analysis was performed for 278 patients with NSTEMI who were hospitalized in The Affiliated Hospital of Qingdao University in 2018 and received long-term follow-up after discharge, and related clinical data were collected to calculate plasma NLR and GRACE score. With the onset of major adverse cardiovascular events (MACE) during follow-up as the endpoint, the patients were divided into MACE group and non-MACE group, and clinical data were compared between the two groups. A multivariate logistic regression analysis was used to investigate the risk factors for MACE, and a receiver operating characteristic (ROC) curve analysis was performed for plasma NLR and GRACE score to investigate their value in eva-luating patient prognosis. The multivariate Cox regression model was used to explore the impact of plasma NLR and GRACE score on the specific survival time of patients. Results There were significant differences between the two groups in age, composition ratio of male patients, composition ratio of diabetic patients, plasma lymphocyte count, plasma NLR, serum low-density lipoprotein cholesterol, plasma B-type natriuretic peptide, left ventricular ejection fraction, and GRACE score (t=-2.748-5.054,χ2=5.067,8.952,Z=-3.108-4.442,P