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Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.

Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.

Authors :
Joanna Domagała-Kulawik
Danuta Wasilewska
Grazyna Hoser
Source :
Folia Histochemica et Cytobiologica, Vol 42, Iss 4, Pp 249-252 (2005)
Publication Year :
2005
Publisher :
Via Medica, 2005.

Abstract

In recent years many data indicate that lymphocytes from cancer patients undergo increased apoptosis. The objective of this study was to evaluate the expression of Fas receptor on lymphocytes obtained from patients with lung cancer. Eighteen patients with non-small cell lung cancer and 18 healthy volunteers were investigated. Expression of Fas (CD95) on CD4+ and CD8+ blood lymphocytes was evaluated by flow cytometry. The proportion of blood Fas+ lymphocytes was significantly higher in lung cancer patients when compared with healthy individuals and in smokers when compared with nonsmokers.

Subjects

Subjects :
Cytology
QH573-671

Details

Language :
English
ISSN :
02398508 and 18975631
Volume :
42
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Folia Histochemica et Cytobiologica
Publication Type :
Academic Journal
Accession number :
edsdoj.59741c9c5e2b450599279f7b93e10add
Document Type :
article
Full Text :
https://doi.org/10.5603/4632