Clinical Monitoring of Serum Levels of Vitamins A, D and E in Children with Recurrent Respiratory Tract Infections of Different Ages: A Clinical Controlled Trial

Rongrong Sun,1 Zhixin Yan,2 Wenxia Yi,2 Wenqiu Tian,2 Mei Sun,2 Jing Zhang1 1Children’s Ward, Cangzhou Central Hospital, Cangzhou, Hebei Province, People’s Republic of China; 2Cangzhou Central Hospital, Cangzhou, Hebei Province, People’s Republic of ChinaCorrespondence: Jing Zhang, Children’s Ward, Cangzhou Central Hospital, Cangzhou City, Hebei Province, 061001, People’s Republic of China, Tel +86 15031730097, Email wuwo681230754@163.comObjective: To study serum levels of vitamins A, D and E in children with recurrent respiratory tract infections of different ages and the correlation.Methods: The clinical data of two groups of children of different ages were collected. The serum levels and deficiencies of vitamins A, D and E in children were statistically analyzed.Results: The proportions of premature infants, low body weight infants, special physique, hospitalization history, hypocalcemia, living in a bungalow, and daily outdoor activities in less than 30 minutes in the case group were higher than those in the control group (χ2=4.507, 5.165, 7.040, 14.907, 4.267, 33.800, 4.507, 8.571, P < 0.05). The serum levels of vitamins A, D and E of children aged 0– 1, 2– 5, and 6– 12 in the case group were lower than those in the control group (P < 0.05). Compared with the control group, the serum vitamin A level of children in the case group was lower (t = 2.631, P < 0.05), and the deficiency rate was higher (χ2=24.200, P < 0.05).Conclusion: Serum levels of vitamins A, D and E, which are related to birth mode, physical fitness, hospitalization history, hypocalcemia, vitamin deficiency, living environment, and daily outdoor activity time, vary in children with recurrent respiratory tract infections of different ages, and are lower in children with recurrent respiratory tract infections than in healthy children.Keywords: different age groups, recurrent respiratory tract infections, children, serum vitamins A, D and E levels, correlation