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Virological failure among people living with HIV receiving second-line antiretroviral therapy in Pune, India
- Source :
- BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-8 (2022)
- Publication Year :
- 2022
- Publisher :
- BMC, 2022.
-
Abstract
- Abstract Background The number of people receiving second-line antiretroviral therapy (ART) has increased as global access to ART has expanded. Data on the burden and factors associated with second-line ART virologic failure (VF) from India remain limited. Methods We conducted cross-sectional viral load (VL) testing among adults (≥ 18 years) who were registered at a publicly funded ART center in western India between 2014 and 2015 and had received second-line ART for at least 6 months. Sociodemographic and clinical characteristics were abstracted from routinely collected programmatic data. Logistic regression evaluated factors associated with VF (defined as VL > 1000 copies/mL). Results Among 400 participants, median age was 40 years (IQR 34–44), 71% (285/400) were male, and 15% (59/400) had VF. Relative to participants without VF, those with VF had lower median CD4 counts (230 vs 406 cells/mm3, p
Details
- Language :
- English
- ISSN :
- 14712334
- Volume :
- 22
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- BMC Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5923988f4c994fd3b3b03e71465c7f98
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s12879-022-07894-2