RESEARCH ON DETERMINATION OF CIRCULATING IMMUNE COMPLEXES IN THE BLOOD OF THE HIGH ECONOMIC VALUE FISH FARMED SPECIES IN ROMANIA

The range of paraclinical investigations applied in ichthyopathology aims at assessing those parameters that can define the pathological modifications and the physiological condition of the fish material, as well as the defense reaction of the unhealthy body. Modification in value of these indicators points out some metabolic perturbations in fish body. Fish have an immunitary system whose complexity and efficiency are directly proportional to their evolution level. That is why, in comparison to the superior vertebrates, the immune reactions of fish body to an antigenic attack are lower, the immune response is weaker and slower, and the quantity of antibodies to form is low. Under the influence of a specific antigen, the immunoformating cells synthetize the corresponding antibodies, determining occurrence of a specific antigen-antibody reaction, resulting in occurrence of the Ag-Ac immune complexes having a role in annihilating and destroying the respective antigens. Formation of immune complexes (CI) is a normal physiological process within the humoral immunity of bodies, representing one of the methods to remove from the body the substances identified as non-self.