Miller Fisher syndrome and cutaneous T-cell lymphoma

The association between Miller Fisher syndrome (MFS) and non-Hodgkin lymphoma is re-ported in a few cases in the current literature. We report a case of a patient known with Mycosis fungoides – cutaneous T cell lymphoma (CTCL) that developed, after 6 years of illness, a variant of Guillain Barré syndrome – Miller Fisher syndrome. The diagnosis was established based on clinical features and positive antiganglioside antibodies (anti GQ1b and antiGT1a antibodies). The neurological involvement in cutaneous T cell lymphoma has been seldom reported and the mechanism is not completely elucidated.