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Microbiome-mediated fructose depletion restricts murine gut colonization by vancomycin-resistant Enterococcus

Authors :
Sandrine Isaac
Alejandra Flor-Duro
Gloria Carruana
Leonor Puchades-Carrasco
Anna Quirant
Marina Lopez-Nogueroles
Antonio Pineda-Lucena
Marc Garcia-Garcera
Carles Ubeda
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Vancomycin-resistant Enterococcus (VRE) represents a major threat for patients’ health. Here, using a mouse model, the authors show that specific commensals restrict VRE gut colonization through depletion of fructose, a nutrient source that boosts VRE growth in vivo.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.57f4e78c2d184b59ac4f9e4bd3c26338
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-35380-5