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Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

Authors :
Yangyang Li
Shichen Su
Yanqing Gao
Guoliang Lu
Hehua Liu
Xi Chen
Zhiwei Shao
Yixi Zhang
Qiyuan Shao
Xin Zhao
Jie Yang
Chulei Cao
Jinzhong Lin
Jinbiao Ma
Jianhua Gan
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

HARP are member of protein-only RNase P, which catalyzes pre-tRNA 5’-end processing and maturation. Here, the authors present crystal structure and provide mechanistic insights into pre-tRNA binding and cleavage by HARP proteins.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.57398d76310a42569bfd77e79f0dc5c3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30072-6