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End-to-side neurorrhaphy in the reconstruction of peripheral segmental neural loss: an experimental study

End-to-side neurorrhaphy in the reconstruction of peripheral segmental neural loss: an experimental study

Authors :
Rafael Silva Lemos
Livia Guerreiro de Barros Bentes
Maria Eduarda dos Santos Lopes Vasconcelos
Daniela Ferreira Tramontin
Luís Vinícius Pires da Costa
Antonio Leonardo Jatahi Cavalcanti Pimentel
Nayara Pontes de Araújo
Mariseth Carvalho de Andrade
Danusa Neves Somensi
Rui Sérgio Monteiro de Barros
Source :
Acta Cirúrgica Brasileira, Vol 39 (2024)
Publication Year :
2024
Publisher :
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2024.

Abstract

ABSTRACT Purpose: To evaluate the effects on peripheral neural regeneration of the end-to-side embracing repair technique compared to the autograft repair technique in Wistar rats. Methods: Fifteen male Wistar rats were divided into three groups with five animals each: denervated group (GD), autograft group (GA), and embracing group (EG). For the evaluation, the grasping test, electroneuromyography (ENMG), and muscle weight assessment were used. Results: Muscle weight assessment and ENMG did not show significant neural regeneration at the end of 12 weeks in the DG and GE groups, but only in GA. The grasping test showed an increase in strength between the surgery and the fourth week in all groups, and only the GA maintained this trend until the 12th week. Conclusions: The present study indicates that the neural regeneration observed in the end-to-side embracing neurorrhaphy technique, in the repair of segmental neural loss, is inferior to autograft repair in Wistar rats.

Details

Language :
English
ISSN :
16782674
Volume :
39
Database :
Directory of Open Access Journals
Journal :
Acta Cirúrgica Brasileira
Publication Type :
Academic Journal
Accession number :
edsdoj.56d444d32fd2467eb4a051792ad1853c
Document Type :
article
Full Text :
https://doi.org/10.1590/acb394024