The Potency of The Cratoxylum cochinchinensis L. Fractional Extract against Some Clinical Methicillin-Resistant Staphylococcus aureus (MRSA) in Viet Nam

Methicillin-resistant Staphylococcus aureus (MRSA) is an important global priority for researching and developing new treatments. Because it takes so much time and money to discover a new antibiotic, the process is becoming more and more challenging. Faced with the above situations, finding new sources of antibiotics or new methods to control antibiotic-resistant bacteria, especially super-resistant varieties, is extremely urgent. For a very long time, medicinal herbs have been utilized to treat infectious disorders. In Vietnam, medicinal plants have been used in treating acute and chronic diseases since ancient times according to traditional medicine prescriptions. Thus, the purpose of this research is to collect the plant extract from medicinal herbs in Vietnam and then the anti-clinical MRSA of the plant extract is determined by the diffusion method. The maceration method is used for collecting the plant extracts. The power of anti-MRSA of plant extracts is determined by the microdilution method. The results show that MIC values of Cratoxylum cochinchinense L. fractional extract against six clinical MRSA in Vietnam are equal to 1.625 mg/mL and 3.250 mg/mL. In addition, the Cratoxylum cochinchinense L. fractional extract expresses the potential of anti-biofilm activity on MRSA ATCC33591.