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Common genetic variation in ETV6 is associated with colorectal cancer susceptibility
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.564a923051f1417ea746e24f251160a4
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms11478