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Serum metabolome associated with severity of acute traumatic brain injury

Authors :
Ilias Thomas
Alex M. Dickens
Jussi P. Posti
Endre Czeiter
Daniel Duberg
Tim Sinioja
Matilda Kråkström
Isabel R. A. Retel Helmrich
Kevin K. W. Wang
Andrew I. R. Maas
Ewout W. Steyerberg
David K. Menon
Olli Tenovuo
Tuulia Hyötyläinen
András Büki
Matej Orešič
CENTER-TBI Participants and Investigators
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Traumatic brain injury is associated with changes to the metabolome. Here the authors show that acute traumatic brain injury has distinctive serum metabolic patterns which may suggest protective changes of systemic lipid metabolism aiming to maintain lipid homeostasis in the brain.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.5647d4f3026c469abc78664e5c748a91
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30227-5