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A Case of Neurotrophic Keratopathy Associated with Nasopharyngeal Carcinoma
- Source :
- Case Reports in Ophthalmology, Vol 9, Iss 1, Pp 114-118 (2018)
- Publication Year :
- 2018
- Publisher :
- Karger Publishers, 2018.
-
Abstract
- Purpose: To report a case of neurotrophic keratopathy associated with nasopharyngeal carcinoma. Case Report: A 59-year-old man who had been diagnosed with a nasopharyngeal carcinoma was referred to the authors because of visual disturbance and pain in his right eye. Slit-lamp examination revealed a corneal epithelial defect and corneal stromal edema surrounding the epithelial defect area in his right eye. Magnetic resonance imaging showed a mass in his cavernous sinus, which was identified as nasopharyngeal carcinoma (NPC). We diagnosed neurotrophic keratopathy associated with NPC and initiated treatment with preservative-free artificial tears, antibiotic eye drops, fibronectin, a therapeutic contact lens, and amniotic membrane transplantation. However, the persistent corneal epithelial defect was unresponsive to these treatments. Conclusion: Neurotrophic keratopathy secondary to NPC is thought to be rare. We presented a case of neurotrophic keratopathy associated with cavernous sinus metastasis of an NPC. The development of new and more effective treatments for this refractory disease is anticipated.
Details
- Language :
- English
- ISSN :
- 16632699
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Case Reports in Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.55ce114d1674f6881aefd89affd15a3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1159/000485965