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The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians

Authors :
Young Jin Kim
Sanghoon Moon
Mi Yeong Hwang
Sohee Han
Hye-Mi Jang
Jinhwa Kong
Dong Mun Shin
Kyungheon Yoon
Sung Min Kim
Jong-Eun Lee
Anubha Mahajan
Hyun-Young Park
Mark I. McCarthy
Yoon Shin Cho
Bong-Jo Kim
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Metabolic traits are heritable intermediate phenotypes widely used in assessing the risk of various diseases. By conducting a genome-wide meta-analysis for metabolic traits in 288,137 East Asians, the authors highlight the interplay of common and rare variants on inherited risk of metabolic traits.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.54d16a2cbba4e25a063ac117c509b5f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34163-2