Back to Search Start Over

Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)

Authors :
Chad ten Pas
Ke Du
Long Pan
Ruo-Qian Wang
Shiyou Xu
Source :
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Abstract A deformable microfluidic system and a fluidic dynamic model have been successfully coupled to understand the dynamic fluid–structure interaction in transient flow, designed to understand the dentine hypersensitivity caused by hydrodynamic theory. The Polydimethylsiloxane thin sidewalls of the microfluidic chip are deformed with air pressure ranging from 50 to 500 mbar to move the liquid meniscus in the central liquid channel. The experiments show that the meniscus sharply increased in the first 10th of second and the increase is nonlinearly proportional to the applied pressure. A theoretical model is developed based on the unsteady Bernoulli equation and can well predict the ending point of the liquid displacement as well as the dynamics process, regardless of the wall thickness. Moreover, an overshooting and oscillation phenomenon is observed by reducing the head loss coefficient by a few orders which could be the key to explain the dentine hypersensitivity caused by the liquid movement in the dentine tubules.

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
20452322
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.54ce586364e9448888894d60c1129330
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-022-24112-w