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Genomic Analysis of Amphioxus Reveals a Wide Range of Fragments Homologous to Viral Sequences

Authors :
Qiao Du
Fang Peng
Qing Xiong
Kejin Xu
Kevin Yi Yang
Mingqiang Wang
Zhitian Wu
Shanying Li
Xiaorui Cheng
Xinjie Rao
Yuyouye Wang
Stephen Kwok-Wing Tsui
Xi Zeng
Source :
Viruses, Vol 15, Iss 4, p 909 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Amphioxus species are considered living fossils and are important in the evolutionary study of chordates and vertebrates. To explore viral homologous sequences, a high-quality annotated genome of the Beihai amphioxus (Branchiostoma belcheri beihai) was examined using virus sequence queries. In this study, 347 homologous fragments (HFs) of viruses were identified in the genome of B. belcheri beihai, of which most were observed on 21 genome assembly scaffolds. HFs were preferentially located within protein-coding genes, particularly in their CDS regions and promoters. A range of amphioxus genes with a high frequency of HFs is proposed, including histone-related genes that are homologous to the Histone or Histone H2B domains of viruses. Together, this comprehensive analysis of viral HFs provides insights into the neglected role of viral integration in the evolution of amphioxus.

Details

Language :
English
ISSN :
15040909 and 19994915
Volume :
15
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Viruses
Publication Type :
Academic Journal
Accession number :
edsdoj.54aca9cb912a4fc58fe0695669b2a77c
Document Type :
article
Full Text :
https://doi.org/10.3390/v15040909