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MD Simulations Reveal Complex Water Paths in Squalene–Hopene Cyclase: Tunnel-Obstructing Mutations Increase the Flow of Water in the Active Site

Authors :
Camilla Gustafsson
Serguei Vassiliev
Charlotte Kürten
Per-Olof Syrén
Tore Brinck
Source :
ACS Omega, Vol 2, Iss 11, Pp 8495-8506 (2017)
Publication Year :
2017
Publisher :
American Chemical Society, 2017.

Subjects

Subjects :
Chemistry
QD1-999

Details

Language :
English
ISSN :
24701343
Volume :
2
Issue :
11
Database :
Directory of Open Access Journals
Journal :
ACS Omega
Publication Type :
Academic Journal
Accession number :
edsdoj.54996684daf84308a61a6dc04a655576
Document Type :
article
Full Text :
https://doi.org/10.1021/acsomega.7b01084