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The Value of Peripheral Blood Leukocyte Parameters in the Early Diagnosis and Clinical Prognosis of Sepsis

Authors :
Yuandan He
Qianqian Liu
Lianhua Wei
Zhipeng Sun
Wenjuan Li
Fangmin Geng
Zhangping Lu
Hongwei Zhang
Source :
International Journal of Analytical Chemistry, Vol 2023 (2023)
Publication Year :
2023
Publisher :
Hindawi Limited, 2023.

Abstract

Background. Early diagnosis of sepsis is the key to timely, targeted treatment. Cell population data (CPD) has been widely used in many diseases, but its predictive value for early diagnosis and the clinical outcome of sepsis remains unclear. Therefore, this paper discusses whether peripheral blood leukocyte parameters can be used as predictive indicators for early diagnosis and the clinical outcome of sepsis. Methods. A retrospective study of 45 patients with sepsis, 53 patients with nonseptic infections, and 86 healthy check-ups admitted to Gansu Provincial Hospital from January 2021 to June 2022 was done using a hematology analyzer. Results. The results of LYMPH#, HFLC#, IG#, NE-WX, LY-WX, LY-WY, and MO-WX showed better diagnostic efficiency in the sepsis group and nonseptic infection group. When the seven differential leukocyte parameters were used to establish diagnostic models, the sensitivity and specificity were 82.20% and 77.40%, respectively. Correlation analysis showed that LYMPH# and HFLC# were positively correlated with PCT (P

Subjects

Subjects :
Analytical chemistry
QD71-142

Details

Language :
English
ISSN :
16878779
Volume :
2023
Database :
Directory of Open Access Journals
Journal :
International Journal of Analytical Chemistry
Publication Type :
Academic Journal
Accession number :
edsdoj.5381cbcbc57c4dfdbcd3a60eca06eaaa
Document Type :
article
Full Text :
https://doi.org/10.1155/2023/6052085