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Long-lasting severe immune dysfunction in Ebola virus disease survivors

Authors :
Aurélie Wiedemann
Emile Foucat
Hakim Hocini
Cécile Lefebvre
Boris P. Hejblum
Mélany Durand
Miriam Krüger
Alpha Kabinet Keita
Ahidjo Ayouba
Stéphane Mély
José-Carlos Fernandez
Abdoulaye Touré
Slim Fourati
Claire Lévy-Marchal
Hervé Raoul
Eric Delaporte
Lamine Koivogui
Rodolphe Thiébaut
Christine Lacabaratz
Yves Lévy
PostEboGui Study Group
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Patients who have recovered from Ebola virus can have ongoing health problems. Here, the authors show that 35 Guinean survivors of the last West African Ebola epidemic have a chronic disease with high inflammatory cytokine expression and other markers of immune activation as well as evidence of intestinal tissue damage nearly two years after their release from hospital.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.525bc83b567f4212a1ba8e49aa100061
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-17489-7