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Existence of traveling wave solutions to data-driven glioblastoma multiforme growth models with density-dependent diffusion

Authors :
Ardak Kashkynbayev
Yerlan Amanbek
Bibinur Shupeyeva
Yang Kuang
Source :
Mathematical Biosciences and Engineering, Vol 17, Iss 6, Pp 7234-7247 (2020)
Publication Year :
2020
Publisher :
AIMS Press, 2020.

Abstract

Mathematical modeling for cancerous disease has attracted increasing attention from the researchers around the world. Being an effective tool, it helps to describe the processes that happen to the tumour as the diverse treatment scenarios. In this paper, a density-dependent reaction-diffusion equation is applied to the most aggressive type of brain cancer, Glioblastoma multiforme. The model contains the terms responsible for the growth, migration and proliferation of the malignant tumour. The traveling wave solution used is justified by stability analysis. Numerical simulation of the model is provided and the results are compared with the experimental data obtained from the reference papers.

Details

Language :
English
ISSN :
15510018
Volume :
17
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Mathematical Biosciences and Engineering
Publication Type :
Academic Journal
Accession number :
edsdoj.518dc25821794afb9fb9425ce045483b
Document Type :
article
Full Text :
https://doi.org/10.3934/mbe.2020371?viewType=HTML