The Role of Alcohols in the Hexene-1 Hydroalkoxycarbonylation Reaction with Catalysts Based on Palladium Complexes

In this work, the activity of various alcohols in the hexene-1 hydroalkoxycarbonylation reaction in the presence of two catalytic systems was investigated for the first time: (1) Pd(PPh3)4-PPh3-TsOH (menthol, cyclohexanol, ethanol, propanol, iso-propanol, butanol, isobutanol and benzyl alcohol) and (2) PdCl2(PPh3)2-PPh3-AlCl3 (ethanol, propanol-1, butanol-1, isoamyl alcohol, isobutanol, pentanol-1, allyl alcohol and tert-butyl alcohol). The optimal process parameters (temperature, pressure and reaction time) for the reactions of the hydropropoxycarbonylation and hydrobutoxycarbonylation of hexene-1, at which the yields of target products reached 91.8% and 91.5%, respectively, were determined.