Back to Search
Start Over
Non-traumatic Acute Epidural Hematoma in Multiple Sclerosis Treated With Fingolimod
- Source :
- Frontiers in Neurology, Vol 10 (2019)
- Publication Year :
- 2019
- Publisher :
- Frontiers Media S.A., 2019.
-
Abstract
- Fingolimod acts as a functional antagonist of the sphingosine-1-phosphate receptor and is widely used for relapsing-remitting multiple sclerosis (MS). Here we report the first case of non-traumatic acute epidural hematoma in a relapsing-remitting MS patient treated with fingolimod. Fingolimod might increase the risk of hemorrhage by enhancing vasospasm and causing vascular disruption. Switching fingolimod to other disease-modifying drugs, including dimethyl fumarate, should be considered when non-traumatic hemorrhage is observed in MS patients.
Details
- Language :
- English
- ISSN :
- 16642295
- Volume :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Neurology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.511b41550b442268e3006870e827632
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fneur.2019.00763