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Depression and incident cardiovascular disease among patients with chronic kidney disease

Authors :
Anthony D'Oro
Devansh Himanshu Patel
Sojin Wass
Trygve Dolber
Khurram Nasir
Mirela Dobre
Mahboob Rahman
Sadeer Al-Kindi
Source :
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 18, Iss , Pp 200199- (2023)
Publication Year :
2023
Publisher :
Elsevier, 2023.

Abstract

Background: Depression is associated with an increased risk of cardiovascular disease (CVD) and is prevalent among patients with chronic kidney disease (CKD). We aimed to identify the association of depression with incident CVD. Methods: We studied patients with CKD stages 2–4 enrolled in the Chronic Renal Insufficiency Cohort (CRIC) and excluded participants with preexisting CVD. The Cox proportional hazard model was used to examine the association between baseline depression [Beck's Depression Inventory (BDI) score ≥11] and incidence of CVD (cerebrovascular accident, myocardial infarction, heart failure, or peripheral artery disease). Models were adjusted for age, sex, race, estimated glomerular filtration rate (eGFR), urine albumin-creatinine ratio (UACR), systolic and diastolic blood pressure, and 10-year estimated CVD risk. Results: Among 2585 CRIC study participants, 640 (25%) patients had depression at study baseline. Compared to patients without depression, patients with depression were more likely to be women (56% vs. 46%), non-White (68% vs. 53%), with household income

Details

Language :
English
ISSN :
27724875
Volume :
18
Issue :
200199-
Database :
Directory of Open Access Journals
Journal :
International Journal of Cardiology. Cardiovascular Risk and Prevention
Publication Type :
Academic Journal
Accession number :
edsdoj.5096965a828d4ae59fe9a225a19a0cf2
Document Type :
article
Full Text :
https://doi.org/10.1016/j.ijcrp.2023.200199