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Effects of a new intravenous electrolyte solution for veterinary therapy on the electrolyte and acid-base balances of healthy horses

Authors :
Priscilla Fajardo Valente Pereira
José Antonio Bessegatto
Gabriela de Castro Bregadioli
Stéfany Lia Oliveira Camilo
Nathali Adrielli Agassi de Sales
Karina Keller Marques da Costa Flaiban
Júlio Augusto Naylor Lisbôa
Source :
Ciência Rural, Iss 0 (2016)
Publication Year :
2016
Publisher :
Universidade Federal de Santa Maria, 2016.

Abstract

ABSTRACT: The effects of a new intravenous electrolyte solution for veterinary therapy on electrolyte and acid-base balances of horses were evaluated, assessing the potential of the use of this solution as a rational alternative in fluid therapy. Eight healthy adult horses, including 4 males and 4 females, received two treatments in a cross-over design: isotonic saline solution (IS) and a test solution (TS) containing 145mEq of Na+, 5mEq of K+, 4mEq of Ca++, 2mEq of Mg++, 96mEq of Cl-, 60mEq of lactate, 50g of dextrose, and 4mg of cyanocobalamin per liter. Solutions were IV infused in a volume corresponding to 5% of BW, over 3 hours. Venous blood samples were taken 5 times before and after the infusion (at 0, 3, 6, 9 e 24h), for pHv, pCO2v, HCO3 -v, BEv, Na+, K+, Cl-, Ca++, Ca, P, Mg, glucose and L-lactate measurements, and AG and SID calculations. The data were analyzed through repeated measures ANOVA. The IS caused mild acidifying effect by increasing Cl- and decreasing plasma SID. In contrast, the TS induced mild and transient hypochloremia without changes in acid-base balance. Hyperglycemia was present at the end of the TS infusion and reversed 6 hours later. The horses did not exhibit any clinical changes. We concluded that TS is an option for fluid therapy in horses.

Details

Language :
English, Portuguese
ISSN :
16784596 and 01038478
Issue :
0
Database :
Directory of Open Access Journals
Journal :
Ciência Rural
Publication Type :
Academic Journal
Accession number :
edsdoj.507c449d47f746119f63e13e055f9a59
Document Type :
article
Full Text :
https://doi.org/10.1590/0103-8478cr20150741