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Effects of a new intravenous electrolyte solution for veterinary therapy on the electrolyte and acid-base balances of healthy horses
- Source :
- Ciência Rural, Iss 0 (2016)
- Publication Year :
- 2016
- Publisher :
- Universidade Federal de Santa Maria, 2016.
-
Abstract
- ABSTRACT: The effects of a new intravenous electrolyte solution for veterinary therapy on electrolyte and acid-base balances of horses were evaluated, assessing the potential of the use of this solution as a rational alternative in fluid therapy. Eight healthy adult horses, including 4 males and 4 females, received two treatments in a cross-over design: isotonic saline solution (IS) and a test solution (TS) containing 145mEq of Na+, 5mEq of K+, 4mEq of Ca++, 2mEq of Mg++, 96mEq of Cl-, 60mEq of lactate, 50g of dextrose, and 4mg of cyanocobalamin per liter. Solutions were IV infused in a volume corresponding to 5% of BW, over 3 hours. Venous blood samples were taken 5 times before and after the infusion (at 0, 3, 6, 9 e 24h), for pHv, pCO2v, HCO3 -v, BEv, Na+, K+, Cl-, Ca++, Ca, P, Mg, glucose and L-lactate measurements, and AG and SID calculations. The data were analyzed through repeated measures ANOVA. The IS caused mild acidifying effect by increasing Cl- and decreasing plasma SID. In contrast, the TS induced mild and transient hypochloremia without changes in acid-base balance. Hyperglycemia was present at the end of the TS infusion and reversed 6 hours later. The horses did not exhibit any clinical changes. We concluded that TS is an option for fluid therapy in horses.
Details
- Language :
- English, Portuguese
- ISSN :
- 16784596 and 01038478
- Issue :
- 0
- Database :
- Directory of Open Access Journals
- Journal :
- Ciência Rural
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.507c449d47f746119f63e13e055f9a59
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/0103-8478cr20150741