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TITAN Project: Microfluidic and Sensing Tools for Immunotherapy

Authors :
Maria Serena Chiriacò
Elisabetta Primiceri
Antonio Turco
Valeria Garzarelli
Giulia Siciliano
Alessia Foscarini
Ahmed Alsadig
Annunziata Carbonara
Benedetta Stampone
Gianluca Trotta
Marco Cereda
Marco de Tullio
Giuseppe Gigli
Francesco Ferrara
Source :
Proceedings, Vol 97, Iss 1, p 214 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

The TITAN project aims to improve immunotherapy, targeting the efficiency of methods to obtain genetically engineered T cells. Immunotherapy has achieved great success in clinical trials, but it is currently very expensive in terms of time required for analysis, reagents, and samples. TITAN aims to the continuous sampling of critical quality attributes, in order to quickly recognize deviations from the desired range and take appropriate corrective actions on process parameters for an optimal outcome. To achieve its aims, TITAN is currently developing microfluidic and sensing tools for the accurate and efficient real-time monitoring of the T cells amplification process.

Details

Language :
English
ISSN :
25043900
Volume :
97
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Proceedings
Publication Type :
Academic Journal
Accession number :
edsdoj.505b7b83344643e9b7e6d4a950c5a3b2
Document Type :
article
Full Text :
https://doi.org/10.3390/proceedings2024097214