Back to Search Start Over

Transplant in Diffuse Large B-Cell Lymphoma

Authors :
Guilherme Duffles
Carmino De Souza
Source :
Brazilian Journal of Transplantation, Vol 25, Iss 2, Pp e0422-e0422 (2022)
Publication Year :
2022
Publisher :
Associação Brasileira de Transplante de Órgãos, 2022.

Abstract

Diffuse large B-cell lymphoma is the most common type of aggressive lymphoma. Patients that don’t respond to first-line therapy have a poor prognosis. Bone marrow transplant represents an effective and established salvage treatment for those patients, with curative potential. Autologous transplant uses the patient stem cell for rescue after high-dose myeloablative chemotherapy, while allogenic transplant relies on a different stem cell for a graft-versus-lymphoma effect. With distinct toxicity and capacity to induce remission, those therapies have great value in the management of patients with relapsed and refractory diffuse large B-cell lymphoma.

Details

Language :
English, Spanish; Castilian, Portuguese
ISSN :
27641589
Volume :
25
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Brazilian Journal of Transplantation
Publication Type :
Academic Journal
Accession number :
edsdoj.50435cb38ade4e5eb4f2b1ed3d412d76
Document Type :
article
Full Text :
https://doi.org/10.53855/bjt.v25i2.445_en