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Transplant in Diffuse Large B-Cell Lymphoma
- Source :
- Brazilian Journal of Transplantation, Vol 25, Iss 2, Pp e0422-e0422 (2022)
- Publication Year :
- 2022
- Publisher :
- Associação Brasileira de Transplante de Órgãos, 2022.
-
Abstract
- Diffuse large B-cell lymphoma is the most common type of aggressive lymphoma. Patients that don’t respond to first-line therapy have a poor prognosis. Bone marrow transplant represents an effective and established salvage treatment for those patients, with curative potential. Autologous transplant uses the patient stem cell for rescue after high-dose myeloablative chemotherapy, while allogenic transplant relies on a different stem cell for a graft-versus-lymphoma effect. With distinct toxicity and capacity to induce remission, those therapies have great value in the management of patients with relapsed and refractory diffuse large B-cell lymphoma.
Details
- Language :
- English, Spanish; Castilian, Portuguese
- ISSN :
- 27641589
- Volume :
- 25
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Brazilian Journal of Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.50435cb38ade4e5eb4f2b1ed3d412d76
- Document Type :
- article
- Full Text :
- https://doi.org/10.53855/bjt.v25i2.445_en