Testing calpain inhibition in tumor endothelial cells: novel targetable biomarkers against glioblastoma malignancy

Authors :: Laura Guarnaccia
Stefania Elena Navone
Laura Begani
Emanuela Barilla
Emanuele Garzia
Rolando Campanella
Monica Miozzo
Laura Fontana
Giovanni Alotta
Chiara Cordiglieri
Chiara Gaudino
Luigi Schisano
Antonella Ampollini
Laura Riboni
Marco Locatelli
Giovanni Marfia
Source :: Frontiers in Oncology, Vol 14 (2024)
Publication Year :: 2024
Publisher :: Frontiers Media S.A., 2024.
Abstract: IntroductionGlioblastoma IDH-wildtype (GBM) is the most malignant brain tumor in adults, with a poor prognosis of approximately 15 months after diagnosis. Most patients suffer from a recurrence in

Subjects :: glioblastoma
angiogenesis
calpains
tumor endothelial cells
target therapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282

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