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The role of the immune system in early-onset schizophrenia: identifying immune characteristic genes and cells from peripheral blood

Authors :
Zi Chen
Yuxue Li
Yao Gao
Xiaoxuan Fan
Xinzhe Du
Xinrong Li
Zhifen Liu
Sha Liu
Xiaohua Cao
Source :
BMC Immunology, Vol 25, Iss 1, Pp 1-12 (2024)
Publication Year :
2024
Publisher :
BMC, 2024.

Abstract

Abstract Background Early-onset schizophrenia (EOS) is a type of schizophrenia (SCZ) with an age of onset of 0.7. Conclusion Our results indicate that immune system function is altered in SCZ. In addition, CCL8, PSMD1, AVPR1B and SEMG1 may regulate peripheral immune cells in EOS. Further, immune characteristic genes and cells are expected to be diagnostic markers and therapeutic targets of SCZ.

Details

Language :
English
ISSN :
14712172
Volume :
25
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Immunology
Publication Type :
Academic Journal
Accession number :
edsdoj.4f865b044744d89ad16f09f40fe9391
Document Type :
article
Full Text :
https://doi.org/10.1186/s12865-024-00618-y