On the reproducibility of TCGA ovarian cancer microRNA profiles.

Authors :: Ying-Wooi Wan
Claire M Mach
Genevera I Allen
Matthew L Anderson
Zhandong Liu
Source :: PLoS ONE, Vol 9, Iss 1, p e87782 (2014)
Publication Year :: 2014
Publisher :: Public Library of Science (PLoS), 2014.
Abstract: Dysregulated microRNA (miRNA) expression is a well-established feature of human cancer. However, the role of specific miRNAs in determining cancer outcomes remains unclear. Using Level 3 expression data from the Cancer Genome Atlas (TCGA), we identified 61 miRNAs that are associated with overall survival in 469 ovarian cancers profiled by microarray (p

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