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Data on the drug release profiles and powder characteristics of the ethyl cellulose based microparticles prepared by the ultra-fine particle processing system

Authors :
Tingting Peng
Yin Shi
Chune Zhu
Disang Feng
Xiangyu Ma
Peipei Yang
Xuequn Bai
Xin Pan
Chuan-yu Wu
Wen Tan
Chuanbin Wu
Source :
Data in Brief, Vol 29, Iss , Pp - (2020)
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Ethyl cellulose (EC) based microparticles (MPs) could provide sustained release for Huperzine A. The drug release mechanism of MPs was exploited to achieve an ideal drug release profile. We previously found that the wettability of MPs greatly contributed to facilitating drug release, which was detailed in a research article entitled “Huperzine A loaded multiparticulate disintegrating tablet: Drug release mechanism of ethyl cellulose microparticles and pharmacokinetic study” (Peng et al., 2019) [1]. In this article, the influence of different polymers and drugs on the drug release behavior was investigated to broaden or compensate this finding. Besides, powder characterization of MPs was used to evaluate the further application of MPs for tablets. Keywords: Microparticles, Drug release profile, Powder characteristic

Details

Language :
English
ISSN :
23523409
Volume :
29
Issue :
-
Database :
Directory of Open Access Journals
Journal :
Data in Brief
Publication Type :
Academic Journal
Accession number :
edsdoj.4e8963ed5bd740f1a298da7dfa8d5c07
Document Type :
article
Full Text :
https://doi.org/10.1016/j.dib.2020.105269