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Association of whole grains intake and the risk of digestive tract cancer: a systematic review and meta-analysis

Authors :
Xiao-Feng Zhang
Xiao-Kai Wang
Yu-Jun Tang
Xiao-Xian Guan
Yao Guo
Jian-Ming Fan
Ling-Ling Cui
Source :
Nutrition Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Publication Year :
2020
Publisher :
BMC, 2020.

Abstract

Abstract Background Several epidemiological studies have investigated the association between whole grains intake and digestive tract cancer risk; however, the results are still controversial. The purpose of this meta-analysis was to assess the association. Methods Studies published before March 2020 were searched in database and other sources. The risk ratio (RR) with the 95% confidence interval (CI) were pooled using fix or random-effects models. Results This meta-analysis included 34 articles reporting 35 studies, 18 studies of colorectal cancer, 11 studies of gastric cancer and 6 studies of esophagus cancer, involving 2,663,278 participants and 28,921 cases. Comparing the highest-intake participants with the lowest-intake participants for whole grains, we found that the intake of whole grains were inversely related to colorectal cancer (RR = 0.89, 95% CI: 0.84–0.93, P

Details

Language :
English
ISSN :
14752891
Volume :
19
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nutrition Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.4e326276661540d1a1c2b7d310d5cd96
Document Type :
article
Full Text :
https://doi.org/10.1186/s12937-020-00556-6