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Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancer

Authors :
Song Li
Wenbin Yu
Fei Xie
Haitao Luo
Zhimin Liu
Weiwei Lv
Duanbo Shi
Dexin Yu
Peng Gao
Cheng Chen
Meng Wei
Wenhao Zhou
Jiaqian Wang
Zhikun Zhao
Xin Dai
Qian Xu
Xue Zhang
Miao Huang
Kai Huang
Jian Wang
Jisheng Li
Lei Sheng
Lian Liu
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Immune checkpoint inhibitors and antiangiogenic agents have shown some activity in patients with late-stage gastric cancer. Here the authors report the results of a phase II trial of neoadjuvant anti-PD1 (camrelizumab), antiangiogenic agent (apatinib), and chemotherapy (S-1 ± Oxaliplatin) in stage T4a/bN + M0 gastric cancer patients.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4e190d3b92f4b949cc25d4b09eb4a42
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-35431-x