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Hierarchical progressive learning of cell identities in single-cell data

Authors :
Lieke Michielsen
Marcel J. T. Reinders
Ahmed Mahfouz
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Classification methods for scRNA-seq data are limited in their ability to learn from multiple datasets simultaneously. Here the authors present scHPL, a hierarchical progressive learning method that automatically finds relationships between cell populations across multiple datasets and constructs a classification tree.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4e15acbcd00048f2abe98c564cc7ece7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23196-8