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STUDY OF THE EFFECT OF LOMUSTIN ON HER2-POSITIVE BREAST CANCER IN FVB/N HER-2 TRANSGENIC MICE
- Source :
- Сибирский онкологический журнал, Vol 18, Iss 5, Pp 54-60 (2019)
- Publication Year :
- 2019
- Publisher :
- Russian Academy of Sciences, Tomsk National Research Medical Center, 2019.
-
Abstract
- Because of the high risk of brain metastases from HER2-positive breast cancer, the study of the anticancer activity of drugs used to treat brain tumors, in particular lomustine, is of great importance. In the FVB/N Her-2 transgenic mice bearing HER2-positive breast cancer (BC HER2+), a single oral administration of lomustine at a dose of 50 mg/kg resulted in a significant tumor growth inhibition (up to 96 %, p
Details
- Language :
- Russian
- ISSN :
- 18144861 and 23123168
- Volume :
- 18
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Сибирский онкологический журнал
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4de6c83be42427f8b4c74e1808c76a0
- Document Type :
- article
- Full Text :
- https://doi.org/10.21294/1814-4861-2019-18-5-54-60