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Insulin resistance limits corneal nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control

Authors :
Georgios Ponirakis
Muhammad A Abdul‐Ghani
Amin Jayyousi
Mahmoud A Zirie
Salma Al‐Mohannadi
Hamad Almuhannadi
Ioannis N Petropoulos
Adnan Khan
Hoda Gad
Osama Migahid
Ayman Megahed
Murtaza Qazi
Fatema AlMarri
Fatima Al‐Khayat
Ziyad Mahfoud
Ralph DeFronzo
Rayaz A Malik
Source :
Journal of Diabetes Investigation, Vol 12, Iss 11, Pp 2002-2009 (2021)
Publication Year :
2021
Publisher :
Wiley, 2021.

Abstract

Abstract Aims/Introduction This study aimed to investigate whether insulin resistance (IR) in individuals with type 2 diabetes undergoing intensive glycemic control determines the extent of improvement in neuropathy. Materials and Methods This was an exploratory substudy of an open‐label, randomized controlled trial of individuals with poorly controlled type 2 diabetes treated with exenatide and pioglitazone or insulin to achieve a glycated hemoglobin

Details

Language :
English
ISSN :
20401124 and 20401116
Volume :
12
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Journal of Diabetes Investigation
Publication Type :
Academic Journal
Accession number :
edsdoj.4da42dc68bbf499e9433d197bed72255
Document Type :
article
Full Text :
https://doi.org/10.1111/jdi.13582