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Applications of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration
- Source :
- International Journal of Molecular Sciences, Vol 25, Iss 11, p 5863 (2024)
- Publication Year :
- 2024
- Publisher :
- MDPI AG, 2024.
-
Abstract
- Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopaedic surgery cases. This review explores the involvement of EVs in nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-free therapies. It underscores the importance of bioengineers comprehending and manipulating EV activity to optimize the efficacy of tissue engineering and regenerative therapies.
Details
- Language :
- English
- ISSN :
- 25115863, 14220067, and 16616596
- Volume :
- 25
- Issue :
- 11
- Database :
- Directory of Open Access Journals
- Journal :
- International Journal of Molecular Sciences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4d7b19ee48e45e3b647660ccac1482c
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/ijms25115863