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A scalable workflow to characterize the human exposome

Authors :
Xin Hu
Douglas I. Walker
Yongliang Liang
Matthew Ryan Smith
Michael L. Orr
Brian D. Juran
Chunyu Ma
Karan Uppal
Michael Koval
Greg S. Martin
David C. Neujahr
Carmen J. Marsit
Young-Mi Go
Kurt D. Pennell
Gary W. Miller
Konstantinos N. Lazaridis
Dean P. Jones
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Humans are exposed to millions of chemicals but mass spectrometry (MS)-based targeted biomonitoring assays are usually limited to a few hundred known hazards. Here, the authors develop a workflow for MS-based untargeted exposome profiling of known and unidentified environmental chemicals.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4d62c49b878b4caf97797da50f1ea5a1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-25840-9