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Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum

Authors :
Emma Puighermanal
Laia Castell
Anna Esteve-Codina
Su Melser
Konstantin Kaganovsky
Charleine Zussy
Jihane Boubaker-Vitre
Marta Gut
Stephanie Rialle
Christoph Kellendonk
Elisenda Sanz
Albert Quintana
Giovanni Marsicano
Miquel Martin
Marcelo Rubinstein
Jean-Antoine Girault
Jun B. Ding
Emmanuel Valjent
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed light into function.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4d48f37c7d94541a98488897d3e9b83
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-15716-9