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The interaction between miRNAs and hazardous materials
- Source :
- Non-coding RNA Research, Vol 8, Iss 4, Pp 507-519 (2023)
- Publication Year :
- 2023
- Publisher :
- KeAi Communications Co., Ltd., 2023.
-
Abstract
- Toxic agents are broadly present in the environment, households, and workplaces. Contamination of food and drinking water with these agents results in entry of these materials to the body. The crosstalk between these agents and microRNAs (miRNAs) affects pathoetiology of several disorders. These agents can influence the redox status, release of inflammatory cytokines and mitochondrial function. Altered expression of miRNA is involved in the dysregulation of several pathophysiological conditions and signaling pathways. These molecules are also implicated in the adaption to environmental stimuli. Thus, the interactions between miRNAs and toxic materials might participate in the hazardous effects of these materials in the body. This review describes the effects of the toxic materials on miRNAs and the consequences of these interactions on the human health.
- Subjects :
- miRNA
Hazardous material
Cancer
Genetics
QH426-470
Subjects
Details
- Language :
- English
- ISSN :
- 24680540
- Volume :
- 8
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Non-coding RNA Research
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4cb5f421eb6a4d9ba97bce6ab8895fef
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.ncrna.2023.06.005