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A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain

Authors :
Ji Wang
Caiguangxi Deng
Ming Liu
Yihao Liu
Liubing Li
Zhangping Huang
Liru Shang
Juan Jiang
Yongyong Li
Ruohui Mo
Hui Zhang
Min Liu
Sui Peng
Haipeng Xiao
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Despite the availability of booster doses against SARS-CoV-2, variants of concern are capable of escaping immune responses established by vaccination or natural infection. In this work, the authors detail the immune responses elicited in a cohort of healthcare workers, receiving a fourth dose of inactivated vaccine.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4c88e33b921047e8a73e8143a1250573
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34633-7