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Phenotype and prognostic factors in geriatric and non‐geriatric patients with transthyretin cardiomyopathy

Authors :
Eugenia Volpentesta
Mounira Kharoubi
Cristiano Donadio
Kahina Rebiai
Pascale Fanen
Benoit Funalot
Thierry Gendre
Vincent Audard
Florence Canoui‐Poitrine
Emmanuel Itti
Emmanuel Teiger
Violaine Planté‐Bordeneuve
Silvia Oghina
Denis Tixier
Sophie Mallet
Amaury Broussier
Thibaud Damy
Amira Zaroui
Source :
ESC Heart Failure, Vol 11, Iss 6, Pp 3814-3832 (2024)
Publication Year :
2024
Publisher :
Wiley, 2024.

Abstract

Abstract Aims Transthyretin cardiac amyloidosis (ATTR‐CM) may be an underestimated cause of heart failure among geriatric patients and represent a unique phenotype and prognostic profile. Methods and results This retrospective, observational, cohort study characterizes cardiac and extracardiac disorders at diagnosis and assesses prognosis among ATTR‐CM patients based on age (geriatric vs. non‐geriatric) and amyloidosis subtype (wild type, ATTRwt and hereditary, ATTRv). In total, 943 patients with ATTR‐CM were included, of which 306 had ATTRv and 637 had ATTRwt. Among these, 331 (35.1%) were non‐geriatric (

Details

Language :
English
ISSN :
20555822
Volume :
11
Issue :
6
Database :
Directory of Open Access Journals
Journal :
ESC Heart Failure
Publication Type :
Academic Journal
Accession number :
edsdoj.4c1079661c08452fbc46f6c108c58253
Document Type :
article
Full Text :
https://doi.org/10.1002/ehf2.14793