Orbital lymphoma: imaging features and differential diagnosis

Abstract Purpose Patterns of orbital lymphoma at diagnosis and follow-up are described. We also discuss differential diagnosis of orbital masses. Materials and methods This pictorial review contains 19 cases of orbital lymphoma before and after treatment. Superior-lateral quadrant and extra-conal location were observed predominantly. Effective response after treatment was presented on follow-up imaging, although few local relapses were found. Further follow-up showed no changes of residual images. Discussion Location of orbital masses can help in the differential diagnosis. Moreover, imaging features of lymphoma at diagnosis can be useful in planning surgical biopsy. Pattern of follow-up described may be relevant on monitoring imaging. Teaching points • Orbital lymphoma involves mainly superior-lateral quadrant and the orbital structures inside. • Location of retrobulbar mass-like lesions are useful information in the differential diagnosis. • Satisfactory response is detected after treatment, however relapse is noted, so follow-up is needed.