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Transient abnormal myelopoiesis: A case series and review of the literature

Authors :
Vandana Baloda
Papagudi G. Subramanian
Yajamanam Badrinath
Ashok Kumar
Pratibha S. Kadam Amare
Shripad D. Banavali
Brijesh Arora
Sumeet Gujral
Source :
Pediatric Hematology Oncology Journal, Vol 2, Iss 1, Pp 14-18 (2017)
Publication Year :
2017
Publisher :
Elsevier, 2017.

Abstract

Transient abnormal myelopoiesis (TAM) is a rare and unique disorder affecting Down syndrome (DS) newborns. This case series presents 5 cases of Down syndrome with TAM diagnosed during 2007–2015 with detailed analysis of immunophenotypic data of each case. CD34, CD13, CD33, CD117, CD41, CD61, CD7 and HLA-DR are useful markers for characterization of blasts of TAM.

Details

Language :
English
ISSN :
24681245
Volume :
2
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Pediatric Hematology Oncology Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.4bac68733e8d4e4d862a49e5186eee5e
Document Type :
article
Full Text :
https://doi.org/10.1016/j.phoj.2017.06.001