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Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis

Authors :
Qiang Yu
Igor Gamayun
Philipp Wartenberg
Qian Zhang
Sen Qiao
Soumya Kusumakshi
Sarah Candlish
Viktoria Götz
Shuping Wen
Debajyoti Das
Amanda Wyatt
Vanessa Wahl
Fabien Ectors
Kathrin Kattler
Daniela Yildiz
Vincent Prevot
Markus Schwaninger
Gaetan Ternier
Paolo Giacobini
Philippe Ciofi
Timo D. Müller
Ulrich Boehm
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

The median eminence (ME) at the base of the brain controls body homeostasis. Here, the authors describe a functional tanycyte subpopulation at the ME which tastes the surrounding milieu, responds to metabolic signals and regulates glucose homeostasis.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4b5c1f7cda5c41f68832e3a28a512ae0
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-37099-3