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Oxidative stress in diverse clinical conditions of SARS-CoV-2 Cuban hospitalized patients
- Source :
- Journal of Pharmacy & Pharmacognosy Research, Vol 11, Iss 1, Pp 63-75 (2023)
- Publication Year :
- 2023
- Publisher :
- GarVal Editorial Ltda., 2023.
-
Abstract
- Context: COVID-19 related to SARS-CoV-2 infection generates inflammation with increased reactive oxygen species production. Drug treatment and others factors could influence systemic oxidative stress during pathogenic insult. Aims: To determine the redox status in COVID-19 patients with different clinical conditions and explore the relationship between redox and hematological hemochemical variables. Methods: In this comparative longitudinal study, blood samples were drawn from 160 individuals divided into four groups: COVID-19 asymptomatic, COVID-19 symptomatic (low and moderate symptoms), COVID-19 convalescent, and presumable healthy subjects. Demographic, redox, hematological, and hemochemical indices were assessed. Statistical analyses compared the median values of each variable and explored individual, simultaneous indices, and multivariate alteration. Results: Relative to the healthy group, acute COVID-19, and convalescent groups had significant differences in global damage indices and antioxidant status (p
Details
- Language :
- English, Spanish; Castilian
- ISSN :
- 07194250
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Pharmacy & Pharmacognosy Research
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4b26ca6fffe749e5bf242df05325415b
- Document Type :
- article
- Full Text :
- https://doi.org/10.56499/jppres22.1535_11.1.63